Adrenomyeloneuropathy (AMN) could affect men and women and normally begins between the ages of 21-35. It is a milder form of the disorder affecting mainly the spinal cord and nerves. Symptoms are usually progressive stiffness, weakness or paralysis of the lower limbs, and ataxia (coordination problems). Although this is normally a more physically symptomatic form, it can result in deterioration of brain function.
Most of the information available about adrenoleukodystrophy is the profound effect it has on males. Little is available about the female symptoms but these can be severe. Some women will have no difficulty, but others can become wheelchair bound with symptoms very similar to adrenomyeloneuropathy.
Female Symptoms
Female carriers (heterozygotes) may experience mild symptoms in later years including progressive stiffness, weakness or paralysis of the lower limbs, ataxia, excessive muscle tone, mild peripheral neuropathy (possible numbness, weakness, burning pain (especially at night), and loss of reflexes) and urinary problems. Some females may go on to suffer more serious symptoms similar to adrenomyeloneuropathy.
Some women take Lorenzo’s Oil and, as in adrenomyeloneuropathy, it seems to hold symptoms at their current level.